Background and objectives: Anal fissure is a painful wound in the anoderm and distal to dentate line, the chronic fissure leads to hypertrophy and fibrosis. In this study, we compared partial and total sphincterotomy in patients with chronic anal fissure. Methods: In this comparative cohort, 100 patients (52 female and 48 male )mean age 43.34 ± 15.28 year...

Anal fissure is an ischemic ulcer that occurs in anoderm and it has no obvious etiology and pathophysiology in current medicine. Anal fissure has a profound history in Persian and Persian medicine and wallflower (Erysimum cheiri (L.) Crantz) has been a common medication in this case. Traditional oil and/or dilute decoction of wallflower has been introduced as an effective topical medic...

Anal fissure is one of the most common anorectal problems. Anal fissure is largely associated with high anal sphincter pressures and most treatment options are based on reducing anal pressures. Conservative management, using increased fiber and warm baths, results in healing of approximately half of all anal fissures. In fissures that fail conservative care, various pharmacologic and surgical o...

background: at present, surgery is the best method for chronic anal fissure, but by acquiring more knowledge about the pathogenesis and function of internal anal sphincter, non surgical treatment such as using of glycerin trinitrate, isosorbide, bethancol, diltiazem and butilinum toxin has been suggested. there is controversy about using of l-arginine. the aim of the present study was to compar...

AIM To evaluate the use of anorectal manometry to select patients for controlled anal dilatation. METHODOLOGY A prospective study was performed using anorectal manometry on all patients with chronic anal fissure who did not have a good response to conservative treatment. Those with increased anal resting pressure were treated with controlled anal dilatation using a two valved anuscope. A seco...

Anal fissure is one of the most common causes of severe anal pain. Factors which predispose people to develop anal fissure include diarrhea, constipation, childbirth, medication as well as constant saddle vibration (amongst professional mountain-bikers) and using a jet of water from a bidet-toilet. For many years, it has been generally accepted that a sphincterotomy, whether surgical or pharmac...

OBJECTIVE To study the association between analfissures and cow's milk allergy (CMA) in infants. METHODS AND METHOD: In a prospective study, 72 confirmed cases of CMA in infants were examined for anal fissure by pediatricians with five years' experience. A positive finding was defined as when an anal fissure was detected by at least two out of three examiners. RESULTS Of infants with CMA with...

2014 Anal fissure is a common painful anorectal condition which affects people of various age groups, and deteriorates their quality of life. Chronic anal fissure requires medical intervention either by pharmacotherapy or by surgery. Various pharmacological agents have been used in the treatment of chronic anal fissure with the aim of relaxation of internal anal-sphincter smooth muscle. Diltiaz...